'it' that is, is what it is'
Welcome to the first of you that have learnt how to navigate the Matrix Book (the Umm el-Kitab). Here you 'true treasure hunters' are beginning to learn what you actually need to get deep into the Superstitions.
There will be lots of dangers in there - you will suffer pestilence, plagues, fires, etc, etc. Don't log off - you got this far. This is a test of your resolve! This is only ONE plant i am talking about - there are millions of others...
i left you with the Bedouin making the 'bread of Light'. This stuff, miraculous as 'IT' is, is free (grow your own).
The Christian Gnostics of Abydos, Egypt, called rue 'Besa', after the dwarf god of transformation and life, called Bes. Bes was associated with the god of al-CHEM-y Ptah.
The Essenes, mentioned earlier, used the plant right up until the time of Christ. Our Blessed Jesu Christos was raised in the Essenic tradition. In the later diaspora of the Christian church the bush had symbolic use in the church, and holy water was sprinkled onto the faithful with branches of rue.
Both Michelangelo and Leonardo da Vinci saw its deeper use, and used it to open their visionary pathways. Da Vinci, in particular, in his writings openly admitted that it was the source of his genius.
It was also featured in al-CHEM-ical traditions as the 'rue of alchemy - a tincture of it mixed with potable gold and acacia gum appears in Samuel Hill Norton's 'Alchemical Key'.
The ancient Etruscans of Italy used rue, along with Phalardis arundinacea (canary reed grass, a source of DMT and 5-MeO-DMT), essential third-eye activators, for both medicine and visionary abilities. Go to this feed AFTER you have read this entire section. And this feed is theirs, not mine - i found understanding of many third-eye openers here. Before you CLICK please READ THE REST on Somanetics and Somagetics.
The ancient Greeks associated it with Hermes and restoration. And Hermes carried his Hermetic staff. This was the symbol on the walls of Perganum, and has been used in folk medicine to ward off the evil eye, even to this day. The hermetic staff provides yogin with the perfect example of kundalini rising - from three and a half coils in the Muladhara (perineum) the ida and pingala wind around the sushumna (which also has a centralised silver coil), activating the chakra centres until Shakti and Shiva are united in the sahasrara. More on yoga later...
It's rue we are on about.
Recent research has been undertaken in the analysis of pinoline and harmine (a related beta-carboline with a 7-methoxy rather than 6-methoxy) and their effects on 3-D material examples of H. sapiens sapiens. This is where it get good. Why weren't we told about these treasures. And this journey into the Superstitions cannot go on without this knowledge.
i am not a CHEM-ist but i have a working knowledge of psychoactives and ethnobotanicals - i have had first-hand experience with these legal plants. Yes all of these plants grow under our very noses, and many examples appear in the Superstitions.
i am here faced with 21 pages hardcopy and no live feed to the source of the document. it was, i daresay, deactivated long ago. i will add notes to these as time permits.
i will only treat one in full then, in the fashion of my mate Gerry the Clown, i will paraphrase the others as time permits.
1 Pinoline for Parkinson's and Alzheimer's Disease
The progression of several neurological diseases such as Alzheimer's disease and Parkinson's disease has recently been shown to involve free radical damage. It is therefore of great importance to find agents that will effectively protect brain tissue against oxidative damage. The purpose of this study suggest that both melatonin and pinoline are valuable as potential free radical scavengers in brain tissue.
Both pinoline and melatonin were found to inhibit lipid peroxidation in a dose-dependant manner.
Frederiksen, T; Pless, G: Anti-oxidative potential of melatonin and pinoline in lipid peroxidation of brain tissue: Master's thesis: I-52, App (1998).
2 Pinoline Cures Dermatosis is Anti-fungal and Anti-bacterial
The extract of Perganum harmala [diff spelllings everywhere] (Rutaceae) was used topically to treat certain dermatoses of inflammatory nature. Results were encouraging and proved the antibacterial, antifungal, antipruritic and probably antiprotozoal effects of the extract.
Perganum harmala: its use in certain dermatoses.
Registry Numbers: 304-21-2 (Harmaline) 442-51-3 (Harmine).
International Journal of Dermatology, El-Saad el-Riaie M, in Int J Dermatol (1980 May) 19 (4): 221-22
3 Radioprotective Effect of Gamma-harmine and its carboline Analogues
Gamma-Harmine (I), harmine (II) and harmaline (III) were isolated from Peganum harmala L. (Zygophylaceae).
Tests were conducted with mice to detect whether gamma-harmine (a new compound), harmine, harmol (IV) and harmalol (V) are effective radioprotective compounds against gamma-ray irradiation.
Intraperitoneal injection of the hydrochlorides of the four alkaloids 50-80 mg.kg-1 X 1 in NIH male mice 30-45 minutes before 8.6 - 9.7 Gy whole body 60Co irradiation significantly increased the survival effects (1.33 - 2.61) and 30-day survival rate in comparison with control mice.
The results indicate that gamma-harmine exhibited relatively good radioprotective effect. gamma-harmine is the first alkaloid isolated from a plant having protective effects against whole-body lethal irradiation in mice.
- Yao Hseuh Hseuh Pao 1995; 30 (9): 715-7. [Article in Chinese] Li GW, Liang PG, Pan GY Cancer Center, Sun-Yat Sen University [中山大學] of Medical Sciences, Guangzhou
4 Harmala and Leukemia
This study was conducted to, one: establish a program to study by in vitro and/or in vivo techniques, the antineoplastic activity of natural plant products and two: to utilize these techniques techniques to study the extracts of two plants, Prunus armeniaca (PA) and Perganum harmala (PH).
Three in vitro procedures:
(a) The growth inhibition of murine P388 leukemia cells in culture;
(b) the assay of cytotoxicity utilizing Cr51 labeled P388 cells;
(c) the assay of P388 colony forming units (CFU) in soft agar were employed and compared with in vivo studies conducted conducted in CD2F1 mice implanted with P388 or L1210 leukemia cells.
The seeds of Perganum harmala were extracted into 70% ethanol and then either extracted into chloroform:
(Phase I) or ultracentrifuged and fractionated
(Phase II) into three fractions:
(b) less than 300,000 MW ('300M') and
(c) less than 100,000 MW ('100M')
When assayed for inhibition of P388 colony forming units (CFU) in soft agar, PH [Perganum harmala] Phase II '300M' showed a marked decrease in CFU with a greater than 98% reduction of CFU at a concentration of 5 ug/ml.
This method was more indicative of follow-up in vivo studies in that it measures both direct cytotoxicity and inhibition of replication. Phase I extracts of PH showed marked increases in lifespan (ILS) of CD2F1 mice bearing P388 tumors (ILS of 36% at a total dose of 300mg/kg) and L1210 tumors (ILS of 33% at a total dose of 300mg/kg). Testing of the fractionated Phase II extract of PH gave evidence to show that the active ingredient is less than 300,000 MW and greater than 100,000 MW.
Diss Abstr Int (SCI), Adams SM, 'The Antineoplastic Effects of Prunus Armeniaca and Peganum harmala in murine P388 and L1210 Leukemia Models in: Diss Abstr Int (Sci) (1983) 44 (4): 1052- B 1983
[i note the Mexican used a lot of PH in his cooking.]
5 Pinoline at same Level as Melatonin in the Eye Retina
The presence of two 5-methoxyindoles, 6-MeO-THBC and melatonin was deomnstrated in human retinae using a highly specific gas chromatographic mass spectrometric method from eyes affected with various ocular diseases. Both compounds were found to occur in similar quantities. 6-MeO-THBC is a newly-identified endogenously-occurring retinal compound possibly acting as a neuromodulator.
Dr M. Leino: 6-Methoxy-tetrahydro-beta-carboline and melatonin in the human retina: Exp Eyes res: 38:3:325-30 (1984) [Ed: this has an important function in the second harmonic generation occurring in the crystal in the 'pineal third-eye' gland. More later...]
6 Beta-carbolines as Anti-oxidants
A series of 1,2,3,4-tetrahydro-beta-carbolines has been synthesized and evaluated for cerebral protecting effects against lipid peroxidation and potassium cyanide intoxication in mice. Most of the compounds synthesized had potent effects against lipid peroxidation. Among them, 1-(3,5-dimethoxyphenyl)-2-propyl-1,2,3,4-tetrahydro-beta-carboline (22) was found to have a combination of potent effects against both lipid peroxidation and potassium cyanide intoxication.
Kawashima Y; Horiguchi A; Taguchi Y; Karasawa Y; Araki H; Hatayama K: 'Synthesis and pharmacological evaluation of 1,2,3,4-tetrahydro-beta-carboline derivatives': Chem Pharm Bulletin (Tokyo): 43:5:783-7 (1995)
7 Pinoline as an Anti-Addictive
Melatonin's active metabolite pinoline is oneirogenic. Not only have such beta-carbolines been shown to have, via the NMDA (N-methyl D-aspartate) glutamate receptor, an anti-addictive effect. [Ed: Important for an alcoholic like me - more later.] It is indicated as an anti-opiate and anti-stimulant (eg cocaine). Note here that the additional rapid-eye movement (REM) sleep for people who are REM-deprived may bring about a 25% increase in serotonin uptake. This additional REM sleep is important for diurnal functioning, and often its lack it is seen as an affliction of drunks and addicts. [More on serotonin later.]
Dr J C Callaway, 'Mechanism for Visions of Dream Sleep', Department of Pharmacology & Toxicology, University of Koupio, Finland
8 Effect of Perganum harmala extract on Root Tips of Allium cepa
Treatment with Perganum harmala extract remarkably increased the mitotic index in Allium cepa root tips with increasing treatment duration at all exposure times used and with almost all concentrations.
The extract caused a relatively high increase in the mitotic index after a long period of treatment with some low concentrations.
Dr SM Abderrahman, Department of Biological Sciences, The Hashemite University, Zarqa, Jordan. Cytobios, 1997; 90 (362-363): 171-4
For more on 'mitotic index' see: http://en.wikipedia.org/wiki/Mitotic_index and Allium cepa is from the 'onion' family.
9 Observations on the Treatment of Natural Haemosporidia Infections by Total Alkaloid of Perganum harmala L. in Cattle
Eighty-two cattle naturally infected with haemosoridians were treated with total alkaloid hydrochoride of Peganum harmale L. [sic] (0.5 mg/kg/day).
Fifty-eight cases with Theileria sergenti showed a cure rate of 86%; thirteen cases with Theileria annulata showed a cure rate of 85%; eight cattle infected with Babesia bigemina showed a cure rate of 88% and three cases of Anaplasma marginale were completely cured.
The results suggested that the curative effect of total alkaloid of P. harmale was better than that of diminazene aceturate and produced minimal side effects. The alkaloid could also be administered to pregnant animals. It was concluded that the total alkaloid of P.harmale showed a marked effect as a treatment for haemosporidian infections in cattle.
For more on these haemosporidians consult the Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?db=genomeprj&cmd=Retrieve&dopt=Overview&list_uids=9543
Hu, T; Fan, B; Liang, J; Zhao, S; Dang, P; Gao, F; Dong, M; Institute of Traditional Chinese Veterinary Medicine, Chinese Academy of Agricultural Sciences, Lanzhou, People's Republic of China, PMID: 9512749, UI: 98173905 [Ed note: with its large population the PRC would have a massive dairy industry, would it not.]
10 Effect of Total Alkaloid of Perganum Harmala L. in the Treatment of Experimental Haemosporidian Infections in Cattle
Cattle experimentally infected with Babesia bigemina or Theileria sergenti or mixed infestations of the two parasites were treated with total alkaloid of Peganum harmala L.
The results showed that treatment was effective against B. bigemina infection, had a marked effect on the course of the infection with T. sergenti and some effect on the course of the mixed infection.
- same group as above.